The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2018
Filed:
Jun. 13, 2016
Applicant:
DE Montfort University, Leicester, Leicestershire, GB;
Inventor:
Bhabatosh Chaudhuri, Leicester, GB;
Assignee:
DE MONTFORT UNIVERSITY, Leicester, Leicestershire, GB;
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0042 (2013.01); C12Y 106/02004 (2013.01); C07K 2319/04 (2013.01);
Abstract
The present invention provides an isolated or recombinant polypeptide comprising or consisting of a modified P450 reductase which lacks N-terminal amino acids relative to the corresponding wild type P450 reductase and comprises an epitope tag comprising the sequence HDEL or KDEL. The modified P450 reductase, when co-expressed with a cytochrome P450, increases the activity and/or expression of the cytochrome P450 compared to the activity and/or expression of the cytochrome P450 when co-expressed with the wild type P450 reductase.