The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2018

Filed:

Jun. 26, 2013
Applicants:

Shenzhen University, Guangdong, CN;

Shenzhen Kangjuzheng Pharmaceutical Technology Co., Ltd, Guangdong, CN;

Inventors:

Guangyi Jin, Guangdong, CN;

Zhulin Wang, Guangdong, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); A61K 47/50 (2017.01); C07K 14/705 (2006.01); A61K 39/00 (2006.01); A61K 39/145 (2006.01); A61K 39/39 (2006.01); C07D 473/18 (2006.01); A61K 47/48 (2006.01); A61K 39/12 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70596 (2013.01); A61K 39/0011 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/39 (2013.01); A61K 47/481 (2013.01); A61K 47/48246 (2013.01); A61K 47/48338 (2013.01); C07D 473/18 (2013.01); C07K 14/4727 (2013.01); A61K 2039/55511 (2013.01);
Abstract

Disclosed is an immune receptor modifier conjugate, obtained from the reaction between a coupling precursor and a biotic ligand, the coupling precursor being a 9-position aminomethyl benzyl purine biotic coupling precursor, and the biotic ligand being selected from one or more of polypeptide, protein, glycoprotein, polysaccharide, polynucleotide, inactivated cells and inactivated microbes. The immune receptor modifier couplet can be used for immunomodulation, antibody preparation, anti-virus, diabetes, tumor immunomodulation, and tumor bio-immunotherapy. The conjugate compounds or salts thereof can be prepared into various therapeutic drugs, and can be prepared into a compound drug together with other drugs, or pharmaceutically acceptable carrier composites or conjugates. Also disclosed are compounds for synthesizing the coupling precursor and salts thereof.


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