The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2018
Filed:
Aug. 01, 2016
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventor:
Khalid Shah, Andover, MA (US);
Assignee:
THE GENERAL HOSPITAL CORPORATION, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 38/17 (2006.01); A61L 27/38 (2006.01); A61L 27/44 (2006.01); A61L 27/58 (2006.01); C12N 15/86 (2006.01); C12N 15/869 (2006.01); A61K 35/28 (2015.01); A61K 35/30 (2015.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61K 47/36 (2006.01); A61L 27/54 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4747 (2013.01); A61K 35/28 (2013.01); A61K 35/30 (2013.01); A61K 38/1761 (2013.01); A61K 38/1774 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 47/36 (2013.01); A61L 27/383 (2013.01); A61L 27/3834 (2013.01); A61L 27/3878 (2013.01); A61L 27/44 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); C12N 9/1205 (2013.01); C12N 15/86 (2013.01); C12Y 207/01145 (2013.01); A01K 2207/12 (2013.01); A61L 2300/416 (2013.01); A61L 2300/64 (2013.01); C07K 2319/55 (2013.01); C07K 2319/61 (2013.01); C12N 2740/15043 (2013.01);
Abstract
Described herein are novel compositions comprising multimodal TRAIL agents and cells engineered to express such multimodal TRAIL agents, including cells encapsulated in a scaffold or matrix, for use in the treatment of disorders such as cancer.