The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2018

Filed:

Mar. 24, 2017
Applicants:

Ihi Corporation, Tokyo, JP;

Yoshihiro Ishikawa, Tokyo, JP;

Inventors:

Yoshihiro Ishikawa, Tokyo, JP;

Haruki Eguchi, Tokyo, JP;

Assignees:

IHI Corporation, Tokyo, JP;

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/28 (2006.01); A61K 31/16 (2006.01); A61K 31/18 (2006.01); A61K 31/15 (2006.01); A61K 31/135 (2006.01); C07F 15/02 (2006.01); A61K 33/00 (2006.01); A61K 33/04 (2006.01); A61K 33/24 (2006.01); A61K 33/32 (2006.01);
U.S. Cl.
CPC ...
C07F 15/025 (2013.01); A61K 31/28 (2013.01); A61K 33/00 (2013.01); A61K 33/04 (2013.01); A61K 33/24 (2013.01); A61K 33/32 (2013.01);
Abstract

[Object] An anticancer agent capable of continuously killing cancer cells in a plurality of phases is provided. [Solution] An anticancer agent contains a complex produced by making a metal-salen complex compound, which includes a central metal and (N, N, O, O) as a quadridentate ligand and is magnetic, bind to taxane molecules which are anticancerous; and the anticancer agent is to kill cancer cells regarding which phase transition of its cell cycle occurs between phases including Gap1, Synthesis, Gap2, and Mitosis and Cytokinesis. The present disclosure is suited for use to kill cancer cells of breast cancer and, particularly, cancer cells of triple-negative breast cancer. The present disclosure is designed to make the anticancer agent contact the cancer cells in two or more continuous phases selected from a group consisting of Gap1, Synthesis, Gap2, and Mitosis and Cytokinesis and kill the cancer cells.


Find Patent Forward Citations

Loading…