logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10030016 B1

PDFFull Text
Date of Patent:
Jul. 24, 2018

Filed:

Dec. 11, 2015

Heterocyclic compounds useful as pdk1 inhibitors

Applicants:

Sunesis Pharmaceuticals, Inc., South San Francisco, CA (US);

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Joseph Arndt, Peabody, MA (US);

Timothy Chan, Newton, MA (US);

Kevin Guckian, Northborough, MA (US);

Gnanasambandam Kumaravel, Westford, MA (US);

Wen-Cherng Lee, Lexington, MA (US);

Edward Yin-Shiang Lin, Chestnut Hill, MA (US);

Daniel Scott, Weston, MA (US);

Lihong Sun, Lexington, MA (US);

Jermaine Thomas, Chelsea, MA (US);

Kurt van Vloten, Bellingham, MA (US);

Deping Wang, Sharon, MA (US);

Lei Zhang, Westford, MA (US);

Daniel Erlanson, San Francisco, CA (US);

Assignees:

Sunesis Pharmaceuticals, Inc., South San Francisco, CA (US);

Millenium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorneys:

Cooley LLP

Heidi A. Erlacher

Ashley M. Dreis

Primary Examiner:

Susanna Moore

Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 239/94 (2006.01); C07D 241/26 (2006.01); C07D 213/82 (2006.01); C07D 213/85 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01); C07D 417/14 (2006.01); C07D 473/34 (2006.01); C07D 491/052 (2006.01); C07D 519/00 (2006.01); C07D 241/28 (2006.01); C07D 498/04 (2006.01); A61P 35/02 (2006.01); A61P 35/04 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/452 (2006.01); A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/497 (2006.01); A61K 31/498 (2006.01); A61K 31/4985 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/5383 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/452 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/498 (2013.01); A61K 31/4985 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/5383 (2013.01); C07D 213/82 (2013.01); C07D 213/85 (2013.01); C07D 241/26 (2013.01); C07D 241/28 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 417/14 (2013.01); C07D 473/34 (2013.01); C07D 487/04 (2013.01); C07D 491/052 (2013.01); C07D 498/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention provides compounds useful as inhibitors of PDK1. The present invention also provides compositions thereof, and methods of treating PDK1-mediated diseases.

Find Patent Forward Citations

Loading…