The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2018

Filed:

Nov. 11, 2014
Applicant:

University of Kansas, Lawrence, KS (US);

Inventors:

Brian S. J. Blagg, Lawrence, KS (US);

Huiping Zhao, Lawrence, KS (US);

Assignee:

UNIVERSITY OF KANSAS, Lawrence, KS (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 413/12 (2006.01); A61K 31/352 (2006.01); A61K 31/4025 (2006.01); A61K 31/453 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 311/16 (2006.01); G16H 50/50 (2018.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/352 (2013.01); A61K 31/4025 (2013.01); A61K 31/453 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 311/16 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); G16H 50/50 (2018.01);
Abstract

Compounds of the formulas: wherein: R-R, X, Y, and A are as defined herein are provided. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds are are useful for the treatment of a disease or disorder. In some embodiments, the disease or disorder is a proliferative disease such as cancer.


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