The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2018

Filed:

Sep. 15, 2014
Applicant:

Dalian University of Technology, Dalian, Liaoning, CN;

Inventors:

Xiaojun Peng, Liaoning, CN;

Si Zhang, Liaoning, CN;

Jiangli Fan, Liaoning, CN;

Jingyun Wang, Liaoning, CN;

Assignee:

DALIAN UNIVERSITY OF TECHNOLOGY, Dalian, Liaoning, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/06 (2006.01); C07D 277/64 (2006.01); C07D 215/10 (2006.01); G01N 1/30 (2006.01);
U.S. Cl.
CPC ...
C07D 277/64 (2013.01); C07D 215/10 (2013.01); C07D 417/06 (2013.01); G01N 1/30 (2013.01);
Abstract

The present invention provides a category of cyano-substituted asymmetric cyanine dyes having the following general structural Formula I and its synthesizing method. The cyano-substituted asymmetric cyanine dyes in present invention are easily synthesized and have long emission wavelength, high molar extinction coefficient, high sensitivity, good light stability, high fluorescence quantum yield after binding with nucleic acid, and low cell toxicity, which is beneficial for application as fluorescent dyes and could also be used in the field of identifying nucleic acid molecules, clinical diagnostics, and immunoassay testing etc.


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