The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2018
Filed:
Jul. 29, 2013
City of Hope, Duarte, CA (US);
Samuel Rahbar, Beverly Hills, CA (US);
James L. Figarola, West Covina, CA (US);
Christopher Lincoln, La Canada, CA (US);
David Horne, Altadena, CA (US);
Rachael Mooney, Duarte, CA (US);
Monika Polewski, Duarte, CA (US);
George Somlo, Seal Beach, CA (US);
Lixin Yang, Arcadia, CA (US);
Sanjay Awasthi, Duarte, CA (US);
CITY OF HOPE, Duarte, CA (US);
Abstract
One aspect of the disclosure relates to derivatives of aryl and heterocyclic ureido aryl and heterocyclic carboxamido isobutyric acids, dichlorophenyl urea, curcumin, and 1,3-diazetidine-2,4-dione, and pharmaceutical compositions thereof. The derivatives disclosed herein can modulate development of adipocytes and various cancer cells, including resistant cancer cells and cancer stem cells. Another aspect of the disclosure relates to the use of the derivatives and pharmaceutical compositions disclosed herein in treatment of obesity and various cancers.