The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2018
Filed:
Feb. 19, 2014
The Regents of the University of California, Oakland, CA (US);
Mitsuko L. Yamamoto, Alameda, CA (US);
Robert H. Schiestl, Encino, CA (US);
Ramune Reliene, Delmar, NY (US);
James Borneman, Riverside, CA (US);
Laura L. Presley, Santa Maria, CA (US);
Jonathan Braun, Tarzana, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Inoculation of ATM-deficient mice with probiotic microorganisms, such as, changed immune parameters, decreased a marker of DNA damage and increased the lifespan of the mice. Compositions and methods described herein are useful for the treatment and prevention of Ataxia telangiectasia and other cancer-prone diseases, such as p53 deficiency-associated cancers. Compositions and methods of the present invention are also useful for treating and preventing radiation-induced toxicity to normal tissue in a subject being exposed to radiation. Compositions and methods of the invention can increase lifespan in a simple, non-invasive manner.