The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2018

Filed:

Sep. 03, 2014
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Elisa E. Konofagou, New York, NY (US);

Tobias Teichert, New York, NY (US);

Vincent P. Ferrera, New York, NY (US);

Fabrice Marquet, New York, NY (US);

Yao-Sheng Teng, New York, NY (US);

Shih-Ying Wu, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 8/00 (2006.01); A61B 8/08 (2006.01); A61N 7/02 (2006.01); A61N 7/00 (2006.01); A61B 90/00 (2016.01);
U.S. Cl.
CPC ...
A61B 8/0808 (2013.01); A61B 8/4281 (2013.01); A61B 8/5223 (2013.01); A61N 7/02 (2013.01); A61B 8/481 (2013.01); A61B 2090/378 (2016.02); A61N 2007/0039 (2013.01); A61N 2007/0052 (2013.01); A61N 2007/0091 (2013.01);
Abstract

Systems and techniques for real-time, transcranial monitoring of safe blood-brain barrier opening include determining an approach angle for targeted blood-brain barrier opening proximate a predetermined region in a brain of a patient, and positioning an ultrasound transducer to generate a focused ultrasound signal at the determined approach angle to the predetermined region in the brain.


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