The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2018

Filed:

Aug. 06, 2012
Applicants:

David T. Wong, Beverly Hills, CA (US);

Wei Liao, North Hills, CA (US);

Inventors:

David T. Wong, Beverly Hills, CA (US);

Wei Liao, North Hills, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 1/40 (2006.01); G01N 33/53 (2006.01); A61B 10/00 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); A61B 10/0051 (2013.01); C12Q 1/68 (2013.01); G01N 1/4005 (2013.01); G01N 33/5306 (2013.01); Y10T 436/2525 (2015.01);
Abstract

Provided herein is an all-in-one saliva collection apparatus that collects saliva to allow for the filtration of saliva in order to separate saliva components, such as extracellular proteins and nucleic acids that are not present in intact cells, from the intact cells and debris remaining in the extracted sample. The filtered saliva samples can be aliquoted into two fractions for protein and/or nucleic acid analysis. The present invention further describes long term storage at ambient temperatures of filtered salivary nucleic acids, and long term storage at ambient temperatures of filtered salivary proteins added to an ethanol solution. The filtered cell-free saliva samples have diagnostic usefulness.


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