The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2018
Filed:
Jun. 08, 2015
Applicant:
Berg Llc, Nashville, TN (US);
Inventors:
Niven Rajin Narain, Cambridge, MA (US);
Rangaprasad Sarangarajan, Boylston, MA (US);
Vivek Kannoth Vishnudas, Bedford, MA (US);
Enxuan Jing, West Roxbury, MA (US);
Assignee:
Berg LLC, Nashville, TN (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 48/00 (2006.01); C12N 15/113 (2010.01); A61K 31/198 (2006.01); A61K 31/7088 (2006.01); A61K 38/08 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/198 (2013.01); A61K 31/7088 (2013.01); A61K 38/08 (2013.01); C12N 2310/11 (2013.01); C12N 2310/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/353 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/3521 (2013.01); C12N 2310/3531 (2013.01); C12N 2320/31 (2013.01); C12N 2320/32 (2013.01);
Abstract
The invention provides HSP90β inhibitors comprising an antisense oligonucleotide targeting HSP90β, pharmaceutical compositions comprising said inhibitors and methods of treatment of a metabolic syndrome by administering said HSP90β inhibitors to a subject in need thereof. The antisense oligonucleotides may be targeted to skeletal muscle.