The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2018
Filed:
Feb. 17, 2015
Marina Biotech, Inc., Bothell, WA (US);
Michael V. Templin, Bothell, WA (US);
Narendra K. Vaish, Kirkland, WA (US);
Kathy L. Fosnaugh, Bellevue, WA (US);
Shaguna Seth, Bothell, WA (US);
Michael E. Houston, Jr., Sammamish, WA (US);
Marina Biotech, Inc., City of Industry, CA (US);
Abstract
This invention provides single-stranded and multi-stranded compounds that are useful in various therapeutic modalities to regulate the expression of nucleic acid molecules in a cell. A range of compounds is provided, each containing one or more conformationally restricted nucleomonomers (CRN). In addition, compounds can contain one or more conformationally restricted nucleomonomers and one or more hydroxymethyl substituted nucleomonomers (unlocked nucleomonomers, UNA).