The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2018
Filed:
May. 21, 2014
Umn Pharma Inc., Akita-shi, Akita, JP;
Timo Vesikari, Tampere, FI;
Vesna Blazevic, Tampere, FI;
Masahiro Okada, Yokohama, JP;
Akiko Mukai, Yokohama, JP;
Tomonori Nishino, Yokohama, JP;
Daisuke Arinobu, Yokohama, JP;
Hiroyuki Ito, Yokohama, JP;
Mamoru Satoh, Yokohama, JP;
UMN PHARMA INC., Akita-shi,Akita, JP;
Other;
Abstract
The present invention aims at establishing a novel means for purifying norovirus VLPs. There is provided a purification method of norovirus virus-like particles, comprising: contacting solution containing norovirus virus-like particles with support for hydroxyapatite chromatography, binding the virus-like particles to the support, subsequently washing the support with buffer, and then eluting the virus-like particles from the support with buffer containing phosphate, wherein the phosphate concentration of the buffer used for elution is less than 10 mM.