The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2018

Filed:

Jun. 23, 2016
Applicant:

Vanderbilt University, Nashville, TN (US);

Inventors:

John P. Wikswo, Brentwood, TN (US);

Dmitry A. Markov, Nashville, TN (US);

Philip C. Samson, Nashville, TN (US);

Frank E. Block, III, Nashville, TN (US);

David K. Schaffer, Nashville, TN (US);

Ronald S. Reiserer, Nashville, TN (US);

Assignee:

VANDERBILT UNIVERSITY, Nashville, TN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/06 (2006.01); A01N 1/02 (2006.01); C12M 3/00 (2006.01); C12M 1/00 (2006.01); C12M 1/32 (2006.01); C12M 1/36 (2006.01); F04B 43/00 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); A01N 1/0247 (2013.01); B01L 3/5027 (2013.01); C12M 23/12 (2013.01); C12M 23/44 (2013.01); C12M 23/58 (2013.01); C12M 29/00 (2013.01); C12M 41/48 (2013.01); F04B 43/0045 (2013.01); B01L 3/502715 (2013.01);
Abstract

The invention relates to a system of fluidic valves and pumps and associated fluidic channels integratable into a bio-object microfluidics module. The module includes input and output buses; upstream and downstream interconnection bus control valves (CVs) coupled to the input and output buses, respectively. It may include arterial, venous, wash and waste bus lines, each connecting between the upstream and downstream interconnection bus CVs. It may also include an input CV connecting to the arterial bus line, upstream interconnection bus CV, bio-object and inlets, and an output CV connecting to the bio-object, input CV, downstream interconnection bus CV and outlets; and a pump connecting between the input CV and bio-object. The system can be arranged to provide MicroFormulator functionality enabling precise mixtures of drugs, chemicals, or biochemicals to be delivered in a time-dependent fashion to biological entities housed in individual wells or chambers.


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