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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10023697 B1

PDFFull Text
Date of Patent:
Jul. 17, 2018

Filed:

Nov. 25, 2016

Condensation polymers for antimicrobial applications

Applicants:

International Business Machines Corporation, Armonk, NY (US);

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Gregory Breyta, San Jose, CA (US);

Julian M. W. Chan, Fremont, CA (US);

Daniel J. Coady, Bluffton, GA (US);

Amanda C. Engler, Woodbury, MN (US);

Jeannette M. Garcia, San Jose, CA (US);

Wei Han, San Jose, CA (US);

James L. Hedrick, Pleasanton, CA (US);

Alshakim Nelson, Montlake, WA (US);

Robert J. Ono, San Jose, CA (US);

Yi Yan Yang, Singapore, SG;

Mu San Zhang, San Jose, CA (US);

Assignees:

International Business Machines Corporation, Armonk, NY (US);

Agency For Science, Technology And Research, Singapore, SG;

Attorney:

Michael R. Roberts

Primary Examiner:

Gregory Listvoyb

Int. Cl.
CPC ...
C08G 73/06 (2006.01); C08G 69/48 (2006.01); C08G 73/02 (2006.01); A01N 43/60 (2006.01); A01N 37/44 (2006.01); A61K 8/88 (2006.01); A61K 31/785 (2006.01); A61K 31/787 (2006.01); A61Q 5/02 (2006.01); A61Q 11/00 (2006.01); A61Q 15/00 (2006.01); C11D 3/48 (2006.01); D21H 17/55 (2006.01); A61Q 17/00 (2006.01); C11D 3/37 (2006.01); A01N 43/40 (2006.01); A01N 37/18 (2006.01); A61K 8/86 (2006.01); A61Q 19/00 (2006.01); A01N 37/12 (2006.01); A01N 37/20 (2006.01); A01N 43/58 (2006.01); A01N 47/06 (2006.01); A61K 8/84 (2006.01); A61K 8/85 (2006.01); C08G 63/91 (2006.01); C08G 64/42 (2006.01); A61K 45/06 (2006.01); D21H 17/56 (2006.01); D21H 21/36 (2006.01); C08L 79/02 (2006.01); C08L 77/04 (2006.01);
U.S. Cl.
CPC ...
C08G 69/48 (2013.01); A01N 37/12 (2013.01); A01N 37/18 (2013.01); A01N 37/20 (2013.01); A01N 37/44 (2013.01); A01N 43/40 (2013.01); A01N 43/58 (2013.01); A01N 43/60 (2013.01); A01N 47/06 (2013.01); A61K 8/84 (2013.01); A61K 8/85 (2013.01); A61K 8/86 (2013.01); A61K 8/88 (2013.01); A61K 31/785 (2013.01); A61K 31/787 (2013.01); A61K 45/06 (2013.01); A61Q 5/02 (2013.01); A61Q 11/00 (2013.01); A61Q 15/00 (2013.01); A61Q 17/00 (2013.01); A61Q 17/005 (2013.01); A61Q 19/007 (2013.01); C08G 63/916 (2013.01); C08G 64/42 (2013.01); C08G 73/024 (2013.01); C08G 73/0206 (2013.01); C08G 73/028 (2013.01); C08G 73/0273 (2013.01); C08G 73/0293 (2013.01); C08G 73/0633 (2013.01); C11D 3/3723 (2013.01); C11D 3/48 (2013.01); D21H 17/55 (2013.01); D21H 17/56 (2013.01); D21H 21/36 (2013.01); A61K 2800/10 (2013.01); A61K 2800/74 (2013.01); C08G 2650/02 (2013.01); C08G 2650/38 (2013.01); C08G 2650/58 (2013.01); C08L 77/04 (2013.01); C08L 79/02 (2013.01);
Abstract

A number of cationic antimicrobial polymers have been synthesized by a condensation polymerization in bulk. The initial polymer formed has backbone tertiary nitrogens, which are subsequently quaternized using a suitable quaternizing agent (e.g., alkyl halide). The cationic polymers include polyamides, polycarbonates, polypolyureas and polyguanidiniums having a cationic repeat unit comprising the quaternary ammonium nitrogen as a backbone nitrogen. The cationic polymers can be active against Gram-negative, Gram-positive microbes, and/or fungi.

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