The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2018
Filed:
May. 19, 2017
Applicants:
Torleif Härd, Uppsala, SE;
Anders Sandberg, Gothenburg, SE;
Inventors:
Torleif Härd, Uppsala, SE;
Anders Sandberg, Gothenburg, SE;
Assignee:
ALZINOVA AB, Gothenburg, SE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/00 (2006.01); G01N 33/53 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4711 (2013.01); A61K 38/00 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/52 (2013.01);
Abstract
The invention provides monomeric and oligomeric amyloid beta peptide isomers that are resistant towards fibrillogenesis and their use as screening reagents or antigens in methods and pharmaceutical preparations for the treatment of Alzheimer's disease and other conditions related to protein misfolding. The invention further provides transgenic animals expressing modified amyloid precursor proteins or amyloid beta peptides.