The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2018

Filed:

Aug. 05, 2015
Applicants:

Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, Jiangsu Province, CN;

Centaurus Biopharma Co., Ltd., Beijing, CN;

Inventors:

Lulu Wang, Lianyungang, CN;

Xiquan Zhang, Lianyungang, CN;

Fei Liu, Lianyungang, CN;

Yizhong Zhu, Lianyungang, CN;

Chao Gao, Lianyungang, CN;

Song Tang, Lianyungang, CN;

Bo Zhu, Lianyungang, CN;

Jianqiu Tang, Lianyungang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
C07D 491/048 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention provides a crystal of 6-arylamino pyridone carboxamide compound and a preparation method thereof. The crystal is obtained by dissolving 6-(2-chloro-4-iodophenylamino)-N-(2-hydroxylethyoxyl)-5-methyl-4-oxo-4,5-dihydrofuro[3,2-c]pyridin-7-carboxamide in an aprotic polar solvent and adding a second solvent thereto. The crystallization method has the advantage of simple and convenient operations, and is beneficial to an industrial production. The resulting crystal has the advantage a high purity and good stability, and is benefit to the manufacture and storage of a medicament containing the same.


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