The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2018

Filed:

May. 26, 2015
Applicant:

Egis Gyogyszergyar Zrt, Budapest, HU;

Inventors:

Ede Laszlo Marvanyos, Budapest, HU;

Attila Virag, Budapest, HU;

Tamas Gregor, Csomor, HU;

Balazs Volk, Budapest, HU;

Maria Tothne Lauritz, Budapest, HU;

Laszlo Pongo, Kerepes, HU;

Balazs Peregi, Pomaz, HU;

Gyula Lukacs, Budapest, HU;

Zoltan Varga, Budapest, HU;

Andras Dancso, Budapest, HU;

Assignee:

EGIS GYOGYSZERGYAR ZRT, Budapest, HU;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); C07B 2200/13 (2013.01);
Abstract

The invention relates to normal or acidic salts of dasatinib and the hydrate and solvate forms thereof. More specifically the invention concerns: dasatinib cyclamic acid salt, dasatinib cyclamic acid (1:1) salt Form I, dasatinib cyclamic acid (1:1) salt Form II, dasatinib hydrogen bromide (1:2) salt, dasatinib methane sulfonic acid (1:2) salt, dasatinib p-toluenesulfonic acid (1:1) dihydrate salt, anhydrous dasatinib p-toluenesulfonic acid (1:1) salt Form I, anhydrous dasatinib p-toluenesulfonic acid (1:1) salt Form II, dasatinib p-toluenesulfonic acid (1:1) salt methanol solvate. Moreover the invention relates process for preparing dasatinib salts, pharmaceutical compositions comprising thereof and the use of dasatinib salts the treatment of cancer.


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