The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2018
Filed:
Mar. 14, 2014
Prometic Biosciences Inc., Laval, CA;
Boulos Zacharie, Laval, CA;
Shaun Abbott, Pointe-Claire, CA;
Lyne Gagnon, Laval, CA;
Pierre Laurin, Ville Mont-Royal, CA;
Brigitte Grouix, Montreal, CA;
PROMETIC PHARMA SMT LIMITED, Cambridge, GB;
Abstract
The present invention relates to compounds of: or a pharmaceutically acceptable salt thereof, wherein A is Calkyl, Calkyl, Calkenyl, Calkenyl, C(O)—(CH)—CHor CH(OH)—(CH)—CHwherein n is 3 or 4; Ris H, F or OH; Ris Calkyl, Calkyl, Calkenyl, Calkenyl, C(O)—(CH)—CHor CH(OH)—(CH)—CHwherein n is 3 or 4; Ris H, F, OH or CHPh; Ris H, F or OH; Q is 1) (CH)C(O)OH wherein m is 1 or 2, 2) CH(CH)C(O)OH, 3) C(CH)C(O)OH, 4) CH(F)—C(O)OH, 5) CF—C(O)OH, or 6) C(O)—C(O)OH; and compositions comprising the same and the method using the same for the prevention or treatment of various fibrotic diseases and conditions in subjects, including pulmonary fibrosis, liver fibrosis, skin fibrosis, renal fibrosis, pancreas fibrosis, systemic sclerosis, cardiac fibrosis or macular degeneration.