The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2018

Filed:

Feb. 03, 2014
Applicant:

Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);

Inventors:

Mark Hayes, Gilbert, AZ (US);

Paul Jones, Mesa, AZ (US);

Stacy Kenyon, Baltimore, MD (US);

Michael Keebaugh, Mesa, AZ (US);

Thomas Taylor, Tempe, AZ (US);

Prasun Mahanti, Tempe, AZ (US);

Sarah Staton, Washington, DC (US);

Noah Weiss, Chandler, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01); G01N 27/453 (2006.01); B03C 7/02 (2006.01); B03C 5/00 (2006.01); G01N 30/00 (2006.01); B03C 5/02 (2006.01); B01L 3/00 (2006.01); G06F 17/50 (2006.01);
U.S. Cl.
CPC ...
B03C 7/023 (2013.01); B01L 3/50273 (2013.01); B01L 3/502707 (2013.01); B03C 5/005 (2013.01); B03C 5/026 (2013.01); G01N 27/44791 (2013.01); G01N 30/0005 (2013.01); G06F 17/5018 (2013.01); B01L 2200/12 (2013.01); B01L 2400/0424 (2013.01); B03C 2201/26 (2013.01);
Abstract

The present invention provides devices and methods to separate and concentrate target species. In some embodiments, a punctuated continuous microchannel or parallel processing (array-based) separations are provided, the microchannel having a plurality of sequential, constrictive insulating features to form a plurality of reservoirs including a first, second and third reservoir, and a plurality of constricted passageways including a first constricted passageway that connects the first reservoir to the second reservoir and a second constricted passageway that connects the second reservoir to the third reservoir. A voltage is applied to the microchannel to create different electrical fields and/or different dielectrophoresis (DEP) gradients at each of the plurality of constricted passageways in order to separate species that have differing ratios of electrokinetic mobility to dielectrophoretic mobility.


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