The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2018
Filed:
Jul. 31, 2014
Circuit Therapeutics, Inc., Menlo Park, CA (US);
Kathryn J. Stahler, Belmont, CA (US);
Greg Stahler, Belmont, CA (US);
Ananya Mitra, Menlo Park, CA (US);
Joyce Huang, Redwood City, CA (US);
Dan Andersen, Menlo Park, CA (US);
Alexander K. Arrow, Lake Forest, CA (US);
David Moore, San Carlos, CA (US);
Circuit Therapeutics, Inc., Menlo Park, CA (US);
Abstract
Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.