The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2018
Filed:
Aug. 19, 2016
Wisconsin Alumni Research Foundation, Madison, WI (US);
The Regents of the University of California, Oakland, CA (US);
Eric A. Johnson, Madison, WI (US);
Sabine Pellett, Madison, WI (US);
William H. Tepp, Stoughton, WI (US);
Tony L. Yaksh, San Diego, CA (US);
Marc Marino, San Diego, CA (US);
Qinghao Xu, San Diego, CA (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.