The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2018

Filed:

Oct. 28, 2016
Applicant:

Biocryst Pharmaceuticals, Inc., Durham, NC (US);

Inventors:

Shanta Bantia, Birmingham, AL (US);

Pravin L. Kotian, Birmingham, AL (US);

Yarlagadda S. Babu, Birmingham, AL (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/196 (2006.01); A61K 31/215 (2006.01); A61K 31/351 (2006.01); A61K 31/7064 (2006.01); A61K 45/06 (2006.01); C07H 7/06 (2006.01); C07D 487/04 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/196 (2013.01); A61K 31/215 (2013.01); A61K 31/351 (2013.01); A61K 31/7064 (2013.01); A61K 45/06 (2013.01); C07D 487/04 (2013.01); C07H 7/06 (2013.01);
Abstract

The present invention is directed to methods and compositions for inhibition of viral nucleic acid polymerases, such as RNA and DNA polymerases, and methods and compositions that are useful for treating viral infections in subjects. The methods comprise administering to the subject a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt or hydrate thereof, or a composition comprising a compound of formula I, or a pharmaceutically acceptable salt or hydrate thereof, and a pharmaceutically acceptable carrier. The composition or method may optionally comprise one or more additional anti-viral agents.


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