The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2018
Filed:
Oct. 29, 2012
Massachusetts Eye & Ear Infirmary, Boston, MA (US);
Ecole Polytechnique Federale DE Lausanne (Epfl), Lausanne, CH;
Konstantina Stankovic, Boston, MA (US);
Demetri Psaltis, Preverenges, CH;
Xin Yang, Renens, CH;
Ye Pu, Ecublens, CH;
Chia-Lung Hsieh, Erlangen, DE;
Massachusetts Eye & Ear Infirmary, Boston, MA (US);
Ecole Polytechnique Federale De Lausanne (EPFL), Lausanne, CH;
Abstract
Systems and methods for imaging ear tissue include: directing illumination radiation to pass through an intact biological structure and be incident on ear tissue that does not include an exogenous fluorophore, at a plurality of locations, the illumination radiation including a plurality of light pulses each having a temporal duration of 500 femtoseconds or less; for each one of the plurality of locations, using a detector to detect radiation emitted from the location that passes through the intact biological structure; and forming an image of the tissue based on the detected radiation at each of the plurality of locations, where the emitted radiation corresponds to endogenous two-photon fluorescence of the tissue.