The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

May. 26, 2017
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Maher Albitar, Sugar Land, TX (US);

Michael J. Keating, Houston, TX (US);

Taghi Manshouri, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/574 (2006.01); G01N 33/564 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); C07K 16/2887 (2013.01); G01N 33/564 (2013.01); G01N 33/57407 (2013.01); G01N 33/57492 (2013.01); G01N 33/6893 (2013.01); C07K 2317/24 (2013.01); C07K 2317/76 (2013.01); G01N 2333/70596 (2013.01); G01N 2800/52 (2013.01); Y10S 424/81 (2013.01); Y10S 436/809 (2013.01); Y10T 436/106664 (2015.01); Y10T 436/107497 (2015.01);
Abstract

The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic antibody:antigen complex, soluble antigen and soluble therapeutic antibody, wherein a patient has undergone at least one course of immunotherapy. Yet further, levels of therapeutic antibody:antigen complexes, soluble antigens or soluble therapeutic antibodies may be measured and used to stage or monitor a hyperproliferative disease.


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