The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Apr. 16, 2015
Applicant:

The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);

Inventors:

Joseph L. Charest, Cambridge, MA (US);

Else Frohlich, Brookline, MA (US);

Christopher DiBiasio, Stoughton, MA (US);

Kenneth Vandevoordt, Medford, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 1/00 (2006.01); G01N 33/00 (2006.01); G01N 33/50 (2006.01); C12M 3/06 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5023 (2013.01); C12M 23/16 (2013.01); C12M 41/00 (2013.01); C12M 41/36 (2013.01);
Abstract

The present disclosure describes systems and methods for mimicking body tissue and the function thereof. The mimicked body tissue can include kidney tissue, the blood brain barrier, and other tissues. In some implementations, the systems described herein are used to test the impact of controlled factors on the tissue. The controlled factors can include flow rates, shear rates, and test chemicals (e.g., therapeutics and toxins). In some implementations, the system and methods are used to test pharmaceutical and biological therapies, characterize healthy or diseased tissue, and observe phenomena of the tissue in vitro.


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