The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Mar. 13, 2013
Applicant:

Acea Biosciences, Inc, San Diego, CA (US);

Inventors:

Xiaobo Wang, San Diego, CA (US);

Xiao Xu, San Diego, CA (US);

Assignee:

ACEA Biosciences, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 27/02 (2006.01); C12M 1/32 (2006.01); C12M 1/34 (2006.01); G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
G01N 27/02 (2013.01); C12M 23/12 (2013.01); C12M 41/36 (2013.01); G01N 27/3276 (2013.01); Y10T 29/49117 (2015.01);
Abstract

A method for assaying target molecules in a sample liquid, the method comprising: providing an impedance monitoring device operably connected to an impedance analyzer; adding a sample liquid suspected of having target molecules to the well thereby permitting binding of target molecules to the capture molecules; monitoring impedance of the well; and determining the presence, amount or concentration of target molecules in the liquid sample from the monitored impedance. The device includes a nonconducting substrate having a well, at least two electrodes fabricated on a bottom of the well and on a same plane, wherein the surfaces of the at least two electrodes are modified with capture molecules configured to bind target molecules in a liquid sample, and at least two connection pads electrically connected to the at least two electrodes.


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