The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2018
Filed:
Jul. 21, 2015
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Patrick Sean Daugherty, Santa Barbara, CA (US);
Kevin Todd Boulware, Pasadena, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); C12N 15/10 (2006.01); G01N 21/64 (2006.01); C07K 14/245 (2006.01); C12Q 1/37 (2006.01); C40B 40/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1044 (2013.01); C07K 14/245 (2013.01); C12N 15/1037 (2013.01); C12Q 1/37 (2013.01); G01N 21/6486 (2013.01); C07K 2319/03 (2013.01); C07K 2319/22 (2013.01); C07K 2319/60 (2013.01); C40B 40/02 (2013.01); C40B 40/10 (2013.01);
Abstract
The present invention provides compositions including peptide display scaffolds that present at least one candidate peptide and at least one detectable moiety in at least one of the N-terminal and C-terminal candidate peptide presenting domains that when expressed in a cell are accessible at a surface of the cell outermembrane. In addition, the present invention also provides kits and methods for screening a library of cells presenting the candidate peptides in peptide display scaffolds to identify a ligand for an enzyme.