The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Apr. 15, 2016
Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Steven Paul Hanlon, Oberwil, CH;

Hans Iding, Rheinfelden, CH;

Paul Spurr, Riehen, CH;

Beat Wirz, Reinach, CH;

Uwe Bornscheuer, Greifswald, DE;

Ioannis Pavlidis, Greifswald, DE;

Martin Steffen Weiss, Greifswald, DE;

Assignee:

HOFFMAN-LA ROCHE INC., Little Falls, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/16 (2006.01); C12N 1/20 (2006.01); C12N 9/10 (2006.01); C12P 13/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1096 (2013.01); C12N 1/16 (2013.01); C12N 1/20 (2013.01); C12P 13/001 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01); C12Y 206/01 (2013.01);
Abstract

The present invention relates to a mutant transaminase with increased transaminase activity relative to the wild-type transaminase, a fusion protein comprising the transaminase, a polynucleotide coding for the transaminase, a host cell comprising the polynucleotide, mutant transaminase and/or fusion protein, a method of producing an amine with the mutant transaminase or fusion protein and the use of the mutant transaminase or fusion protein for the production of an amine.


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