The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Dec. 16, 2011
Applicants:

Pauline Mclean Quigley Sheldon, Seattle, WA (US);

Peter S. Gagnon, San Clemente, CA (US);

Gina Nichols, Everett, WA (US);

Barbara A. Thorne, Sammamish, WA (US);

Inventors:

Pauline McLean Quigley Sheldon, Seattle, WA (US);

Peter S. Gagnon, San Clemente, CA (US);

Gina Nichols, Everett, WA (US);

Barbara A. Thorne, Sammamish, WA (US);

Assignee:

GENZYME CORPORATION, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C07K 14/005 (2013.01); C12N 15/86 (2013.01); C12N 2750/14151 (2013.01);
Abstract

Provided herein are methods for the purification of recombinant adeno-associated virus (rAAV) vectors that can be used for gene transfer and specifically for gene therapy or vaccination. Recombinant AAV vectors of the invention are substantially free of in-process impurities, including production components such as cellular nucleic acids, cellular proteins, helper virus, and media components.


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