The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Jun. 03, 2014
Applicant:

Mogam Biotechnology Institute, Yongin-si, Gyeonggi-do, KR;

Inventors:

Mihee Hwang, Yongin-si, KR;

Kukjin Park, Yongin-si, KR;

Duckhyang Shin, Yongin-si, KR;

Hyeon Lee, Yongin-si, KR;

Sooin Kim, Yongin-si, KR;

Eunyoung Cho, Yongin-si, KR;

Misuk Kim, Yongin-si, KR;

Dong Ho Ahn, Yongin-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 39/00 (2006.01); A61K 39/145 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0686 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); C12N 7/00 (2013.01); C12N 2500/92 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16151 (2013.01); C12N 2760/16152 (2013.01); C12N 2760/16234 (2013.01); C12N 2760/16251 (2013.01); C12N 2760/16252 (2013.01);
Abstract

The present invention relates to a novel MDCK-derived cell line capable of being suspension-cultured in a protein-free medium and a method for proliferating a virus using the MDCK-derived cell line to produce a vaccine. The novel MDCK-derived cell line exhibits high and uniform productivity for various viruses, while causing less viral antigenic variations with low tumorigenicity, and thus can be useful in producing viruses used for vaccines.


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