The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Nov. 04, 2014
Applicants:

Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;

Institut Curie, Paris, FR;

Universite Paul Sabatier Toulouse Iii, Toulouse, FR;

Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;

Inventors:

Aurellen Olichon, Toulouse, FR;

Sandrine Moutel, Paris, FR;

Franck Perez, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 50/06 (2006.01); C07K 16/00 (2006.01); C07K 16/32 (2006.01); C07K 16/44 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
C07K 16/005 (2013.01); C07K 16/32 (2013.01); C07K 16/40 (2013.01); C07K 16/44 (2013.01); C07K 2317/22 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C07K 2317/80 (2013.01); C07K 2317/92 (2013.01); C40B 50/06 (2013.01);
Abstract

The invention relates to the identification of a highly stable single domain antibody scaffold (hs2d Ab) and its use in generating synthetic single domain antibody library (hs2d Ab-L1). The invention also relates to antigen-binding proteins comprising said stable single domain antibody scaffold and their uses, in particular as therapeutics.


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