The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Aug. 25, 2015
Applicants:

Ustav Organicke Chemie a Biochemie Av Cr, V.v.i., Praha, CZ;

Fyziologicky Ustav Av {hacek Over (C)}r, V.v.i., Praha, CZ;

Inventors:

Eva Kudova, Praha, CZ;

Hana Chodounska, Praha, CZ;

Vojtech Kapras, Praha, CZ;

Ladislav Vyklicky, Kamenice, CZ;

Karel Vales, Praha, CZ;

Ullrich Jahn, Praha, CZ;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/18 (2006.01); C07J 43/00 (2006.01); C07J 53/00 (2006.01); C07J 9/00 (2006.01); C07J 41/00 (2006.01); C07C 305/20 (2006.01); C07C 59/80 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); C07C 59/80 (2013.01); C07C 305/20 (2013.01); C07D 213/18 (2013.01); C07J 9/005 (2013.01); C07J 41/0033 (2013.01); C07J 53/001 (2013.01); C07C 2603/26 (2017.05);
Abstract

Amphiphilic compounds with tetradecahydrophenanthrene skeleton and their enantiomers, exhibiting neuroprotective effects, their use in methods of treatment of neuropsychiatric disorders associated with an imbalance in glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post-traumatic stress disorder and diseases related to stress, anxiety, schizophrenia and psychotic disorders, pain, addiction, multiple sclerosis, epilepsy, glioma, and a pharmaceutical composition containing compound.


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