The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Aug. 27, 2015
Applicant:

Prexton Therapeutics SA, Geneva, CH;

Inventors:

Delphine Charvin, Gex, FR;

Baptiste Manteau, Lingolsheim, FR;

Vincent Pomel, Groisy, FR;

François Conquet, Beaumont, FR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 495/04 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 31/5377 (2013.01);
Abstract

The present invention provides a novel chromone oxime derivative of formula (I), which is a modulator of nervous system receptors sensitive to glutamate and, furthermore, presents an advantageously high brain penetration upon oral administration. The invention also relates to a pharmaceutical composition containing this compound, and to its use for the treatment or prevention of conditions associated with altered glutamatergic signalling and/or functions, or conditions which can be affected by alteration of glutamate level or signalling, particularly acute and chronic neurological and/or psychiatric disorders.


Find Patent Forward Citations

Loading…