The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2018
Filed:
May. 18, 2017
The Brigham and Women's Hospital, Inc., Boston, MA (US);
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, National Institute of Health, Washington, DC (US);
Asaf Alimardanov, North Bethesda, MD (US);
Gregory D. Cuny, Houston, TX (US);
Gurmit S. Grewal, Lexington, MA (US);
Arthur Lee, San Jose, CA (US);
John C. McKew, Boyds, MD (US);
Agustin H. Mohedas, Somerville, MA (US);
Min Shen, Boyds, MD (US);
Xin Xu, Potomac, MD (US);
Paul B. Yu, Boston, MA (US);
Abstract
The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds may also be used to reduce circulating levels of ApoB-100 or LDL and treat or prevent acquired or congenital hypercholesterolemia or hyperlipoproteinemia; diseases, disorders, or syndromes associated with defects in lipid absorption or metabolism; or diseases, disorders, or syndromes caused by hyperlipidemia.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile