The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2018
Filed:
Aug. 26, 2016
Applicant:
Blueprint Medicines Corporation, Cambridge, MA (US);
Inventors:
Steven Mark Wenglowsky, Cambridge, MA (US);
Natasja Brooijmans, Boston, MA (US);
Chandrasekhar V. Miduturu, Cambridge, MA (US);
Neil Bifulco, Jr., Sudbury, MA (US);
Assignee:
BLUEPRINT MEDICINES CORPORATION, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01);
Abstract
This disclosure relates to inhibitors of NTRK that are active against wild-type NTRK and its resistant mutants, such as compounds of Formula (I):