The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Feb. 06, 2015
Applicant:

The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);

Inventors:

Christopher N. Bowman, Boulder, CO (US);

Christopher J. Kloxin, Newark, DE (US);

Weixian Xi, Boulder, CO (US);

Tao Gong, Denver, CO (US);

Sankha Pattanayak, Denver, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/34 (2006.01); C07D 239/47 (2006.01); C07D 239/54 (2006.01); C07D 473/18 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6876 (2018.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C07D 473/34 (2013.01); C07D 239/47 (2013.01); C07D 239/54 (2013.01); C07D 473/18 (2013.01); C12N 15/1048 (2013.01); C12N 15/1093 (2013.01); C12Q 1/6802 (2013.01); C12Q 1/6876 (2013.01);
Abstract

Click thiol-X monomers and polymers containing such monomers are disclosed. The clickable sequence controllable monomers include an optionally protected thiol moiety; an optionally protected Michael acceptor moiety; a primary functional side chain and one ore more secondary functional side chains. A clickable sequence controllable monomer, can have the structure: wherein independently Y and Z are atoms having a valence electrons of 3 or more; n is a integer from 0-10; m is a integer from 0-10; x is a integer from 0-10; PFS is a functional group SFSi; SFS2; and SFS3 are independently a combination of hydrogen, hydroxyl, aromatic, amine, carboxyl, and carbonyls, optionally substituted to form hydrophilic, hydrophobic, amphiphilic, or charged (positive or negative or both) side chains; T is an optionally protected thiol; and TCA is an optionally protected thiol-click acceptor. Methods of using such polymers are also disclosed.


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