The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2018
Filed:
Oct. 27, 2015
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Nigel Liverton, Harleysville, PA (US);
Scott D. Kuduk, Harleysville, PA (US);
Douglas Beshore, Lower Gwynedd, PA (US);
Yunfu Luo, Shanghai, CN;
Na Meng, Shanghai, CN;
Tingting Yu, Shanghai, CN;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention is directed to piperidine isoxazole and isothiazole orexin compounds which are antagonists of orexin receptors. Such compounds are of the general structural formula I: wherein the variables are defined herein. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the prevention or treatment of such diseases in which orexin receptors are involved.