The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Feb. 06, 2015
Applicant:

Boston Biomedical, Inc., Cambridge, MA (US);

Inventors:

Toshihiko Sone, Osaka, JP;

Wataru Hirose, Osaka, JP;

Naoaki Shimada, Osaka, JP;

Chiang J. Li, Cambridge, MA (US);

Wei Li, Wayland, MA (US);

David Leggett, Milton, MA (US);

Assignee:

Boston Biomedical, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/92 (2006.01); A61K 31/343 (2006.01); C07D 413/06 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); A61K 31/497 (2006.01); A61K 31/443 (2006.01);
U.S. Cl.
CPC ...
C07D 307/92 (2013.01); A61K 31/343 (2013.01); A61K 31/443 (2013.01); A61K 31/497 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 413/06 (2013.01);
Abstract

The present invention provides a compound of the following Formula (1) or a pharmaceutically acceptable salt thereof: wherein X is an oxygen atom and the like; Y is —CO—, —SO— and the like; Ris an optionally-substituted Calkyl group, an optionally-substituted Calkylcarbonyl group and the like; Ris an optionally-substituted Calkyl group, an optionally-substituted Calkoxy group, an optionally-substituted amino group, an optionally-substituted 5- to 12-membered monocyclic or polycyclic saturated heterocyclic group and the like; R, R, R, and Rare independently a hydrogen atom and the like which exhibits excellent effects in suppressing the proliferation and sphere-forming ability of cancer cells, and can be useful as an antitumor drug or cell growth inhibitor.


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