The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Aug. 08, 2012
Applicants:

Adam W. York, Princeton, NJ (US);

Prabhas V. Moghe, Basking Ridge, NJ (US);

Kathryn E. Uhrich, Plainfield, NJ (US);

Robert Prud'homme, Lawrenceville, NJ (US);

Inventors:

Adam W. York, Princeton, NJ (US);

Prabhas V. Moghe, Basking Ridge, NJ (US);

Kathryn E. Uhrich, Plainfield, NJ (US);

Robert Prud'homme, Lawrenceville, NJ (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 49/00 (2006.01); G01N 33/92 (2006.01); A61L 27/18 (2006.01); A61L 27/54 (2006.01); A61L 29/16 (2006.01); A61L 31/16 (2006.01); A61K 9/51 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 49/0093 (2013.01); A61K 9/513 (2013.01); A61K 47/542 (2017.08); A61K 47/6425 (2017.08); A61K 47/6907 (2017.08); A61K 49/0082 (2013.01); A61L 27/18 (2013.01); A61L 27/54 (2013.01); A61L 29/16 (2013.01); A61L 31/16 (2013.01); G01N 33/92 (2013.01); A61K 9/14 (2013.01); A61K 9/141 (2013.01); A61K 9/51 (2013.01); A61L 2300/44 (2013.01); A61L 2300/442 (2013.01); A61L 2300/624 (2013.01); A61L 2400/12 (2013.01);
Abstract

The present invention relates to nanoparticle compositions and treatment of cardiovascular disease using nanoparticles to target Class A and B scavenger receptors. This invention further relates to methods of detecting cells that express scavenger receptors, detecting atherosclerotic lesions, and targeting bioactive amphiphilic macromolecules to cells that express scavenger receptors.


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