The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Aug. 14, 2017
Applicant:

Reform Biologics, Llc, Cambridge, MA (US);

Inventors:

David S. Soane, Palm Beach, FL (US);

Robert P. Mahoney, Newbury, MA (US);

Philip Wuthrich, Belmont, MA (US);

Daniel G. Greene, Belmont, MA (US);

Assignee:

Reform Biologics, LLC, Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 47/54 (2017.01); C08G 73/02 (2006.01);
U.S. Cl.
CPC ...
A61K 47/543 (2017.08); A61K 38/00 (2013.01); C08G 73/0233 (2013.01);
Abstract

The invention encompasses therapeutic formulations comprising a protein active ingredient and a stabilizing excipient, methods of improving stability in a therapeutic formulation comprising a protein active ingredient by adding a stability-improving amount of a stabilizing excipient to the therapeutic formulation, and methods of reducing adverse infusion-related effects in a patient, comprising administering to a patient in need thereof a therapeutic formulation comprising a protein active ingredient and a stabilizing excipient.


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