The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Dec. 01, 2015
Applicant:

Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

Inventors:

Dong-Chul Pyun, Tucson, AZ (US);

Theodore J. Price, Tucson, AZ (US);

Gregory D. Dussor, Tucson, AZ (US);

Dipti Tillu, Tucson, AZ (US);

Bo Lian, Tucson, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/05 (2006.01); A61K 31/155 (2006.01); A61K 31/4365 (2006.01); A61K 31/7056 (2006.01); A61K 31/4375 (2006.01); A61K 31/4439 (2006.01); A61K 31/616 (2006.01); A61K 38/22 (2006.01); A61K 38/02 (2006.01); A61K 38/20 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2264 (2013.01); A61K 31/05 (2013.01); A61K 31/155 (2013.01); A61K 31/4365 (2013.01); A61K 31/4375 (2013.01); A61K 31/4439 (2013.01); A61K 31/616 (2013.01); A61K 31/7056 (2013.01); A61K 38/02 (2013.01); A61K 38/185 (2013.01); A61K 38/204 (2013.01);
Abstract

Methods and compositions using a combination of adenosine monophosphate protein kinase (AMPK) activators for treating pain such as post-surgical pain or development of chronic pain. The two or more AMPK activators work synergistically and may be administered in individually sub-efficacious doses. The AMPK activators may have different mechanisms of AMPK activation. The AMPK activators may be administered systemically and/or topically in, for example, as a gel, ointment, cream, lotion, suspension, liquid, or transdermal patch.


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