The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2018
Filed:
May. 02, 2016
Applicant:
Dnatrix, Inc., Houston, TX (US);
Inventors:
Ramon Alemany Bonastre, Barcelona, ES;
Juan Jose Rojas Exposito, Barcelona, ES;
Manel Maria Cascallo Piqueras, Barcelona, ES;
Assignee:
DNATRIX, INC., Houston, TX (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/761 (2015.01); C12N 7/01 (2006.01); C12N 15/861 (2006.01); C12N 15/11 (2006.01); C12N 15/34 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 2710/10021 (2013.01); C12N 2710/10032 (2013.01); C12N 2710/10043 (2013.01); C12N 2710/10321 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10343 (2013.01); C12N 2820/007 (2013.01);
Abstract
The invention relates to an oncolytic adenovirus for the treatment of cancer, containing a human DNA sequence isolating a promoter conferring selective expression on an adenoviral gene. Said adenovirus can also contain a sequence that optimizes the protein translation of an adenoviral gene regulated by a promoter conferring tumor selectivity. The invention is suitable for use in the treatment of cancer.