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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10016463 B1

PDFFull Text
Date of Patent:
Jul. 10, 2018

Filed:

Jul. 30, 2013

Treatment of pulmonary arterial hypertension with prostacyclin-treated endothelial progenitor cells

Applicant:

United Therapeutics Corporation, Silver Spring, MD (US);

Inventors:

Roger Jeffs, Chapel Hill, NC (US);

Thomas Petersen, Durham, NC (US);

Roger M. Ilagan, Burlington, NC (US);

Michael Wade, Chapel Hill, NC (US);

Assignee:

United Therapeutics Corporation, Silver Spring, MD (US);

Attorney:

Foley & Lardner LLP

Primary Examiner:

Blaine Lankford

Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61K 35/44 (2015.01); A61K 31/5585 (2006.01); A61K 35/28 (2015.01); A61K 45/06 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61K 35/44 (2013.01); A61K 31/5585 (2013.01); A61K 35/28 (2013.01); A61K 45/06 (2013.01); C12N 5/0692 (2013.01); C12N 2501/999 (2013.01); F04C 2270/041 (2013.01);
Abstract

The current application is directed to a method for treating pulmonary arterial hypertension (PAH), comprising: providing isolated endothelial progenitor cells (EPCs); treating the EPCs with prostacyclin, wherein the treated EPCs exhibit a hyperproliferative phenotype with enhanced angiogenic property; and administering a composition comprising the treated EPCs into a subject suffering from PAH.

Find Patent Forward Citations

Jeffs, Roger. (2018). Treatment of pulmonary arterial hypertension with prostacyclin-treated endothelial progenitor cells (U.S. Patent No. 10016463). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10016463

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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