The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Dec. 04, 2012
Applicant:

Cohera Medical, Inc., Pittsburgh, PA (US);

Inventors:

Dottie Clower, Pittsburgh, PA (US);

Despina Dobbins, Gibsonia, PA (US);

Stephanie Kladakis, Pittsburgh, PA (US);

Assignee:

Cohera Medical, Inc., Raleigh, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/765 (2006.01); A61K 31/80 (2006.01);
U.S. Cl.
CPC ...
A61K 31/80 (2013.01); F04C 2270/0421 (2013.01);
Abstract

A tissue sealant that includes the reaction product of (a) a polyol; (b) a polyisocyanate; and (c) an alkoxy silane having the formula: (RRR)—Si—CH—Z where (i) Z is an —OH, —SH, —NCO, or —NHRgroup, where Ris hydrogen, an alkyl group, or an aryl group; and (ii) each R, R, and R, independently, is H, an alkoxy group, an alkyl group, a heteroalkyl group other than an alkoxy group, an aryl group, or a heteroaryl group, with the proviso that at least two of R, R, and Rare alkoxy groups, the relative amounts of the polyol, polyisocyanate, and alkoxy silane being selected such that the reaction product comprises free isocyanate groups. The tissue sealant is moisture-curable and biodegradable in a physiological environment.


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