The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2018
Filed:
Dec. 18, 2015
The Catholic University of Korea Industry-academic Cooperation Foundation, Seoul, KR;
Mi La Cho, Seoul, KR;
Chul Woo Yang, Seoul, KR;
Jong Young Choi, Seoul, KR;
Sung Hwan Park, Seoul, KR;
Min Jung Park, Seoul, KR;
Seon Yeong Lee, Seoul, KR;
Joo Yeon Jhun, Seoul, KR;
Eun Jung Lee, Namyangju-si, KR;
Jae Kyung Kim, Cheonan-si, KR;
Eun Kyung Kim, Seoul, KR;
Sun Woo Lim, Seoul, KR;
Abstract
Provided is a composition for alleviating nephrotoxicity caused by an immunosuppressive drug, including metformin, and a composition for preventing or treating an immune disease, including the same. Further, the composition provided can be useful in improving a treatment effect on diseases requiring immunosuppression by effectively alleviating a decline in renal function caused due to side effects of conventional immunosuppressive drugs, and can also be useful in preventing or treating organ transplant rejection, autoimmune diseases, inflammatory diseases and the like since various methods of co-administering a conventional immunosuppressive drug and metformin are suggested to reduce nephrotoxic side effects of conventional immunosuppressive drugs and maximize immunosuppressive or immunomodulatory effects.