The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2018

Filed:

Feb. 28, 2014
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);

Inventors:

Yosef Mandel, Givataim, IL;

Ismail E Araci, Palo Alto, CA (US);

Stephen R Quake, Stanford, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 3/16 (2006.01); A61B 5/00 (2006.01); A61B 8/08 (2006.01); A61B 5/03 (2006.01); A61B 90/00 (2016.01);
U.S. Cl.
CPC ...
A61B 3/16 (2013.01); A61B 5/6821 (2013.01); A61B 90/361 (2016.02); A61B 2576/00 (2013.01);
Abstract

Glaucoma is the second most common cause of blindness in the global world. It is a multifactorial disease with several risk factors, of which intraocular pressure (IOP) is the most important. IOP measurements are used for glaucoma diagnosis and patient monitoring. IOP has wide diurnal fluctuation, and is dependent on body posture, so the occasional measurements done by the eye care expert in clinic can be misleading. We provide an implantable sensor, based on microfluidic principles, which in one example has 1 mmHg limit of detection, high sensitivity and excellent reproducibility. This sensor has an optical interface, which enables IOP to be read with, for example, a cell phone camera. The design, fabrication, along with the option of self-monitoring are promising steps toward better patient care and treatment for this devastating disease.


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