The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Dec. 23, 2013
Applicant:

University of Tromsø, Tromsø, NO;

Inventors:

Jon Florholmen, Tromsø, NO;

Trine Olsen, Tromsø, NO;

Renathe Rismo, Tromsø, NO;

Rasmus Goll, Tromsø, NO;

Guanglin Cui, Tromsø, NO;

Assignee:

UNIVERSITY OF TROMSØ, Tromsø, NO;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 33/00 (2006.01); A61K 39/00 (2006.01); G01N 33/566 (2006.01); G01N 33/68 (2006.01); C12Q 1/6883 (2018.01); G06F 19/00 (2018.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6863 (2013.01); C12Q 1/6883 (2013.01); G01N 33/5088 (2013.01); G01N 33/6893 (2013.01); G06F 19/345 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/525 (2013.01); G01N 2333/54 (2013.01); G01N 2333/57 (2013.01); G01N 2800/065 (2013.01); G01N 2800/52 (2013.01); G01N 2800/54 (2013.01); G01N 2800/56 (2013.01);
Abstract

The present invention provides a method of determining whether a patient with inflammatory bowel disease (IBD) and who has been treated with anti TNFα therapy is in immunological remission (IR), said method comprising determining the level of a cytokine selected from TNFα, IL-17 and IFN-y in a Gl mucosal sample from said patient. Also provided are methods of prognosis and treatment using said method of determination, in particular discontinuing treatment if said patient is in IR and continuing treatment if said patient is not in IR.


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