The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 2018
Filed:
Jul. 15, 2015
Applicant:
Miltenyi Biotec Gmbh, Bergisch Gladbach, DE;
Inventors:
Assignee:
Miltenyi Biotec, GmbH, Bergisch Gladbach, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); G01N 33/569 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56966 (2013.01); C07K 14/705 (2013.01); C12N 5/0081 (2013.01); G01N 2333/70596 (2013.01);
Abstract
A process for depleting host cells from a xenograft of human cells on a murine host is disclosed. The process includes fragmenting the xenograft, subjecting the sample to antibodies specific for a murine CD9 epitope coupled to a detection means, depleting the cell suspension from cells bound by the CD9-antibodies using the detection means, and collecting the cells not bound by the CD9-antibodies as target cells.